Startropics

StarTropics is a video game released by Nintendo in 1990 for the NES. It was released only in North America and Europe. StarTropics was followed by a sequel entitled Zoda's Revenge: StarTropics II, released in 1994.

Original description:

Tropical adventure of epic dimensions!

A teenagers dream vacation on a tranquil south sea island...A shooting star!?...It's an omen of disaster! Mike's archeologist uncle has been kidnapped. Mike alone can rescue him. Thus begins the test of island courage.
Happy villagers eagerly assist, but endless enemies threaten every step. Mike's search leads him through the lush wilderness of the StarTropics. As he travels on foot, or by submarine through this sunny land of dark secrets and deadly peril, Mike is a tireless fighter.
Using common sense, an island yo-yo, magic potions, and mysterious new weapons and skills, Mike must defend himself. Restore his strength with coconut milk. Help him defeat starnge creatures, sea monsters and hidden attackers.
Join Mike in his adventure. Journey to the StarTropics.
Modern-day adventure in an island paradise!

Instructions

Enter - start (pause);    Arrows - move;
Space - checks health and chapter, change main weapon;
Z - jump, talk, inspect objects;
X - attack, submerge Sub-C;

You can change keyboard settings, save (F5) and load (F8) the game.
Put your mouse over the game and choose your settings, you can also play the game in fullscreen.